We will be making other videos from the 2019 ANZAED Conference available shortly. Watch this space!
Keynote Abstract: Novel brain directed treatments in anorexia nervosa
Anorexia nervosa is a disabling and deadly disorder. Talking therapies are somewhat effective, but treatment innovations are urgently needed, especially for adults with severe and enduring illness. Given improved understanding of the brain circuitry involved in anorexia nervosa, a diverse range of novel brain directed treatments are emerging as potential adjuncts to treatment of this disorder, which have different degrees of invasiveness/reversibility. These include cognitive trainings (e.g. cognitive remediation therapy), novel medications (e.g. oxytocin, ketamine), non-invasive brain stimulation [e.g. repetitive transcranial magnetic stimulation (rTMS), transcranial direct current stimulation (tDCS)], neurofeedback, and neurosurgical methods (e.g. deep brain stimulation, stereotactic ablation). I will review what is known about the efficacy, mechanisms of action, treatment targets/protocols, safety profiles, scalability and ethical considerations relevant to these different approaches. I will present examples from our own work, such as our recent sham-controlled trial of rTMS in severe enduring anorexia nervosa.
Professor Ulrike Schmidt (MD PhD FRCPsych) is Professor of Eating Disorders and Head of the Department of Psychological Medicine at the Institute of Psychiatry, Psychology and Neuroscience at King’s College London (KCL) as well as a Consultant Psychiatrist at the Eating Disorders Service at the South London and Maudsley NHS Foundation Trust (SLaM).
Professor Schmidt was a member of the NICE Eating Disorders Guidelines development group, chair of the Section of Eating Disorders at the Royal College of Psychiatrists, and a board member of the Academy for Eating Disorders.
Professor Schmidt’s work has been recognized through the receipt of several prestigious awards including the 2005 National Health Service Award for Innovative Service Delivery; the 2009 Academy for Eating Disorders Leadership Award for Clinical, Educational and Administrative Service; the 2013 KCL Supervisory Excellence Award; the 2014 Hilde Bruch Award for Outstanding Achievements in Eating Disorders Research and Treatment; the British Medical Journal’s 2017 Mental Health Team of the Year Award; and the NIHR Senior Investigator Award. Professor Schmidt has published some 330 peer-reviewed papers and 90 other publications on eating disorders, including text books, chapters, patient manuals, and web-based treatment or training packages.